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Brooke T Mossman Selected Research

Serpentine Asbestos (Chrysotile)

12/2018Mechanistic in vitro studies: What they have told us about carcinogenic properties of elongated mineral particles (EMPs).
5/2011Osteopontin modulates inflammation, mucin production, and gene expression signatures after inhalation of asbestos in a murine model of fibrosis.
9/2008Inhaled asbestos exacerbates atherosclerosis in apolipoprotein E-deficient mice via CD4+ T cells.
2/2007Airway epithelial NF-kappaB activation modulates asbestos-induced inflammation and mucin production in vivo.
1/2007Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice.
11/2005Gene expression profiles reveal increased mClca3 (Gob5) expression and mucin production in a murine model of asbestos-induced fibrogenesis.
4/2004Dose-Response Relationships in Expression of Biomarkers of Cell Proliferation in in vitro Assays and Inhalation Experiments.

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Brooke T Mossman Research Topics

Disease

24Neoplasms (Cancer)
12/2018 - 08/2002
24Inflammation (Inflammations)
12/2018 - 02/2002
23Mesothelioma
12/2018 - 02/2002
21Malignant Mesothelioma
01/2016 - 07/2003
13Lung Diseases (Lung Disease)
01/2016 - 05/2002
12Lung Neoplasms (Lung Cancer)
12/2018 - 08/2002
10Pneumonia (Pneumonitis)
01/2016 - 05/2002
9Asbestosis
01/2016 - 03/2003
9Fibrosis (Cirrhosis)
03/2015 - 06/2002
8Carcinogenesis
03/2015 - 09/2004
7Silicosis
01/2018 - 05/2002
6Lung Injury
06/2007 - 05/2003
5Pulmonary Fibrosis (Fibrosing Alveolitis)
02/2012 - 05/2002
4Hyperplasia
12/2018 - 08/2002
2Chronic Obstructive Pulmonary Disease (COPD)
01/2016 - 06/2006
2Infections
08/2013 - 07/2006
2Asthma (Bronchial Asthma)
05/2011 - 06/2006
2Carcinoma (Carcinomatosis)
01/2011 - 09/2004
1Ovarian Neoplasms (Ovarian Cancer)
10/2020
1Metaplasia
12/2018
1Idiopathic Pulmonary Fibrosis
01/2018
1Multiple Sclerosis
01/2016
1Gout
01/2016
1Alzheimer Disease (Alzheimer's Disease)
01/2016
1Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
11/2014
1Necrosis
09/2013
1Interstitial Lung Diseases (Interstitial Lung Disease)
05/2011
1Eosinophilia
05/2011
1Myeloperoxidase Deficiency
06/2009
1Atherosclerosis
09/2008

Drug/Important Bio-Agent (IBA)

38AsbestosIBA
01/2016 - 02/2002
11CytokinesIBA
01/2016 - 02/2002
10Crocidolite Asbestos (Blue Asbestos)IBA
05/2013 - 03/2003
9Silicon Dioxide (Silica)FDA LinkGeneric
01/2016 - 05/2002
7Serpentine Asbestos (Chrysotile)IBA
12/2018 - 04/2004
7InflammasomesIBA
01/2016 - 05/2008
6Oxidants (Oxidizing Agents)IBA
12/2018 - 02/2002
5Doxorubicin (Adriamycin)FDA LinkGeneric
11/2014 - 12/2010
5Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA
11/2011 - 03/2003
5Transcription Factor AP-1 (Transcription Factor AP 1)IBA
09/2008 - 11/2002
4CarcinogensIBA
12/2018 - 12/2002
4MineralsIBA
12/2018 - 02/2010
4ChemokinesIBA
01/2016 - 01/2006
4NF-kappa B (NF-kB)IBA
09/2008 - 05/2002
3DNA (Deoxyribonucleic Acid)IBA
12/2018 - 11/2002
3Proteins (Proteins, Gene)FDA Link
09/2012 - 12/2002
3Phosphotransferases (Kinase)IBA
11/2011 - 05/2005
3ErbB Receptors (EGF Receptor)IBA
11/2011 - 08/2002
3MucinsIBA
05/2011 - 06/2006
3Transcription Factors (Transcription Factor)IBA
09/2008 - 06/2006
3Pharmaceutical PreparationsIBA
03/2007 - 12/2002
2Telomerase (Telomerase Reverse Transcriptase)IBA
12/2018 - 11/2011
2Particulate MatterIBA
01/2016 - 05/2008
2Environmental Pollutants (Pollutants, Environmental)IBA
01/2016 - 05/2008
2Interleukin-1 Receptors (Interleukin 1 Receptor)IBA
01/2016 - 08/2013
2Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA
11/2014 - 11/2009
2Mitogen-Activated Protein Kinase 7IBA
11/2014 - 04/2013
2MesothelinIBA
09/2013 - 09/2012
2AcidsIBA
09/2013 - 03/2007
2AgarIBA
04/2013 - 11/2002
2Messenger RNA (mRNA)IBA
12/2007 - 11/2003
2Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
09/2005 - 05/2005
1TalcFDA Link
10/2020
1Heparan Sulfate Proteoglycans (Heparan Sulfate Proteoglycan)IBA
01/2018
1Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link
01/2016
1CollagenIBA
01/2016
1Tyrosine Kinase InhibitorsIBA
11/2014
1vandetanib (ZD6474)IBA
11/2014
1QuartzIBA
09/2013
1Chemokine CCL5IBA
04/2013
1Cisplatin (Platino)FDA LinkGeneric
04/2013
1Bovine Serum AlbuminIBA
09/2012
1Mitogen-Activated Protein Kinase 1 (p42 MAP Kinase)IBA
11/2011
1TOR Serine-Threonine KinasesIBA
11/2011
1U 0126 (UO 126)IBA
09/2011
1OsteopontinIBA
05/2011
1alpha2 Subunit Collagen Type IIBA
05/2011
1Amphibole AsbestosIBA
09/2010
1PhosphotyrosineIBA
05/2010
1Tyrosine (L-Tyrosine)FDA Link
05/2010
1Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
05/2010
1ZeolitesIBA
02/2010
1erioniteIBA
02/2010
1LipopolysaccharidesIBA
06/2009
1titanium dioxide (Titania)FDA Link
09/2008
1ApolipoproteinsIBA
09/2008
1Apolipoproteins E (ApoE)IBA
09/2008
1LigandsIBA
02/2008
1fos-related antigen 1IBA
02/2008
1Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
02/2008
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
02/2008
1Carrier Proteins (Binding Protein)IBA
06/2007
1tetraethylene glycolIBA
03/2007
1Sulfhydryl Compounds (Thiols)IBA
03/2007
1Lipid AIBA
03/2007

Therapy/Procedure

5Therapeutics
01/2016 - 07/2003
2Injections
09/2013 - 07/2011
1Microspheres (Microsphere)
09/2013
1Bone Marrow Transplantation (Transplantation, Bone Marrow)
01/2008
1Intranasal Administration
03/2007